Multipolar Neuron

Time To Read

1 minute

Date Last Modified

Histological slide showing multiple blue-stained multipolar neurons with large cell bodies, dendrites, and axons against a pink-stained background.
Figure 1: Histological section showing multiple blue-stained multipolar neurons with extensive dendrites and axons, set against a pink-stained neural tissue background.

A multipolar neuron is a type of neuron characterized by its shape.  Most multipolar neurons considered in an introductory A&P class are interneurons or motor neurons. These neurons are the most common shape found in the central nervous system (CNS).

Histological slide showing the boundary between gray and white matter, with numerous cell bodies in the gray matter and densely packed axons in the white matter.
Figure 2: Histological section showing the boundary between gray and white matter, with numerous neuron cell bodies in the gray matter and densely packed axons in the white matter.

The term “multipolar” refers to the multiple dendrites extending from the cell body.  In a multipolar neuron, the cell body is opposite of the axon terminals. This differs from a unipolar neuron. In a unipolar neuron, the cell body comes off the axon. It is separate from the dendrites. The cell body terminates at the axon hillock, an area of resistance for action potentials.  If an action potential generates enough current to crest the axon hillock, it will be propagated down the axon. Then, it will reach the axon terminals.

It is quite rare to find any good picture of a multipolar neuron fully stretched out. We would see these as we do in diagrams.    In this picture here, the unmyelinated neuron cell bodies and axons are stained a dark  purple.  There are representations of transversely cut axons and the tear-drop shaped cell bodies with the point at the axon hillock.

Figure 1: Cerebrum, axons and neuron cell bodies 40X Slide 076b
Figure 2:Cerebellum, H&E, 20X Slide 077
All by University of Michigan Histology, licensed under CC BY-NC-SA 3.0.

List of terms