Renal Tubule

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Microscopic view of kidney renal medulla histology with a light purple stain. The image is closely packed with circular and curved tubules, which are labeled as PCTs, DCTs, Loops of Henle, and Collecting Duct. The tubules are arranged in a tight formation. Cell nuclei are visible within the tubule walls as small, dark dots.
Figure 1: Kidney renal medulla with labeled PCT, DCT, Loop, and Collecting Duct tubules.

PCT

The proximal convoluted tubule is made of simple cuboidal cells with lots of villi. These villi are needed to reabsorb the many items that have escape filtration in the glomerulus.

Nephron Loop

The neprhon loop is divided into the ascending and desceding limb of the loop. The loop of a juxtamedullary nephron dips deeper into the medullary pyramid than the loop of a cortical nephron. Each limb of the loop has a thick segment. It is made of simple cuboidal cells. There is also a thin segment, which is made up of simple squamous epithelial cells.

DCT

The distal convoluted tubule, as other parts of the nephron, is made up of simple cuboidal epithelial cells. The diameter of the DCT is larger than the diameter of the PCT or the loop. The DCT, like the PCT, has villi on the apical surface of its cells. However, there are fewer villi on these cells than on the cells of the PCT.

Collecting Duct

The collecting duct collects filtrate from many nephrons, not just one. Therefore the collecting ducts have the largest diameter of all the 2D circles you see in the kidney. Collecting ducts have two populations of cells. Principle cells are tasked with managing reabsorption or secretion of sodium whereas the intercalated cells are tasked with managing pH.

A high-magnification microscopic image of kidney medulla tissue. The tissue is stained with a pink/purple hue, revealing cellular structures and dark red blood cells. Tubular structures form circular and elongated shapes with white empty lumens inside. Several of these loops are highlighted with thin yellow circles, drawing attention to their structure within the tissue. The composition is dense, showing the intertwining relationship between tubules and capillaries.
Figure 2: Microscopic view of Nephron Loops in Kidney Medulla, circled in yellow.
Histological image of the renal medulla. Collecting ducts appear as circular lumens surrounded by epithelial cells with dark nuclei, stained pink/purple. Two collecting ducts are highlighted with yellow circles and labeled "CD". The image is a close-up, emphasizing cellular structures and staining patterns.
Figure 3: Renal medulla: kidney collecting ducts marked with yellow circles.
Diagram illustrating the kidney structure, featuring simple cuboidal and simple squamous epithelial cells, a medullary pyramid, and a frontal section of the right kidney.
Diagram illustrating the kidney structure, featuring simple cuboidal and simple squamous epithelial cells, a medullary pyramid, and a frontal section of the right kidney.

Figure 1: Kidney monkey Slide 210 PAS stain
Figure 2: Kidney monkey Slide 206
Figure 3: Kidney monkey Slide 210 H&E stain
All by University of Michigan Histology, licensed under CC BY-NC-SA 3.0.

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