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OVERVIEW
PART 1
PART 2
PART 3
PART 4
PART 5
PART 6
PART 7
Quiz
CHART CLUE
Stina’s bloodwork over the years shows sky-high inflammatory markers – even between attacks, when she looks fine. It is a chemistry clue everyone explained away. This module introduces the molecular cast of her disease, each member riding in on its biomolecule class.
The Story
Stina’s entire disease comes down to one protein folded the wrong way. Before we can see how a protein gets its shape – or loses it – we need to know what holds moleculesGroups of atoms bonded together. together. Three bonds do most of the work: covalent (sharing), ionic (transfer), and the weak but decisive hydrogen bond that helps fold proteinsLarge molecules made of amino acids with various functions in the body..
From Stina’s chart: Around this point Stina started reading about her own body — teaching herself the chemistry her doctors kept waving off. She didn’t have the diagnosis yet, but she had the stubbornness to keep asking what the molecules were doing.
Compare Stina’s uninfected appendixA small, finger-like pouch attached to the cecum, thought to play a role in immune function. to an infected appendix.
Activity:
Activity:
Some of those bonds make waterThe universal solvent essential for life. itself behave strangely – and water sets the body’s pHA measure of hydrogen ion concentration in a solution., where Stina’s urate story really begins.
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Acids, Bases & the Water of Life
List of terms
- molecules
- proteins
- appendix
- water
- pH