Salivary Glands

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2–3 minutes

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Location of 3 Glands

There are three pairs of salivary glands: the parotid, sublingual, and submandibular glands. The parotid gland, near the ear, is the largest. The sublingual gland is beneath the tongue, and the submandibular gland is lower in the jaw. These glands produce saliva, which is primarily water and slightly acidic, containing enzymes like amylase and antibodies for immune defense. Salivary glands consist of serous cells (producing watery secretions) and mucous cells (producing mucus).


Saliva

Saliva is primarily water. It is slightly acidic owing to these four things listed below. Yes, you have growth factors in your saliva. These factors encourage mitosis and turnover of the stratified squamous keratinized epithelium of the mouth. You have antibodies mostly IgAs that are common to saliva and other secretions of the body. Your saliva does contain enzymes, it contains more than these enzymes listed here. Lipase is an enzyme that is capable of performing chemical digestion on lipids. There are two kinds of lipase, one that is capable of acting at relatively neutral pH levels. This lipase is found in your saliva and begins the chemical digestion of lipids. There was also a lipase that works at a much lower pH. The pancreas secretes this lipase into the small intestine. Here, it finishes digesting the lipids that the salivary lipase started. A lysozyme is an enzyme that functions more in encouraging innate immunity then it does in chemical digestion.  Isozymes are able to breakdown a protein called peptidoglycans that is present in bacterial plasma membranes.


Histology

The Histology of salivary glands is deceptively simple. We are at the point in this course where we must identify structures we have already seen. We need to also identify structures in histological pictures. Present in this picture above are many arterials and capillaries. I can recognize some by their tunica intima and smooth muscle. I can recognize others by these little red blood cells. There are ducts through which the saliva is collected and distributed into the mouth. Ducks are usually lined by simple or stratified cuboidal cells and there is a collection of ducts right down here. There are two cell types that are specific to salivary glands. Serous cells secrete a watery secretion and this bulk of cells up here are serous cells. There are also mucus cells that secrete a more viscous product with a higher pH. These cells have a more puff like appearance and do not take up the stain as readily as the serous cells


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