Sinusoidal Capillaries

Time To Read

1–2 minutes

Date Last Modified

Found in the bone marrow and liver, these capillaries are permeable to red and white blood cells.

Tunica Externa

Absent

Tunica Media

Absent

Tunica Interna (Intimia)

The simple squamous epithelial cells of these capillaries have the largest intercellular clefts (spaces between the cells). These clefts make these capillaries the most permeable of the three types.  In sinusoidal capillaries, the intercellular clefts are extremely large. Entire cells such as erythrocytes (red blood cells) and leukocytes (white blood cells) can fit in these clefts.  Red blood cells and white blood cells are created in red bone marrow. This marrow is found in flat bones such as those in the sternum and coxal bones (hips).  Sinusoidal capillaries allow these newly formed cells to leave the bone marrow and enter into circulating blood.

Lumen

Big enough for only one erythrocyte

High-magnification light microscopy image of a bone marrow sinusoid. Numerous hematopoetic cells, stained eosinophilic and basophilic, pack the field. The sinusoid appears as a clear space with a thin endothelial lining and connects to the surrounding tissue; its irregular borders are visible. Cellular nuclei appear as dark spots.
Figure 1: Bone marrow capillary (sinusoid) with blood cells, viewed under a microscope. Red and purple staining.

Figure 1: Slide 48b Fetal leg, cross section, Masson stain
All by University of Michigan Histology, licensed under CC BY-NC-SA 3.0.

List of terms