Endocrine Histology General Information

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The endocrine system is an unconnected collection of organs that secrete hormones, or chemical messengers into systemic circulation.  These hormones travel in the blood. Some are soluble, while others are not. They are received by distant organs with specific receptors that match the desired hormones.  In this way, one organ can exert specific control over another organ.  

Endocrine organs are defined by the ability to secrete chemical messengers or hormones.  Many endocrine organs are members of other organ systems as well.  Reproductive organs such as the ovary and the testes are also endocrine organs.  The hypothalamus is located deep within the brain. It is known as a neuroendocrine organ. This indicates its dual membership in the nervous system and the endocrine system.  The pancreas secretes the hormones insulin and glucagon as a member of the endocrine system. It also secretes many digestive enzymes as part of the digestive system.  ​

The organs that secrete these chemical messengers are the main players of the endocrine system. Equally important are the effectors, or the tissues and organs, that have receptors for hormones.  These target organs are the effectors that produce a characteristic response when the connection is made between hormone and receptor.  The pancreas can make insulin all day long. However, it does not benefit someone whose cells no longer have receptors for insulin.  In this way, all organs of the body partake in the endocrine system as target organs.

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