Spinal Cord with DRG Slide 065-1c

Histological slide of a dorsal root ganglion stained purple, showing clusters of large, round neuronal cell bodies with centrally or eccentrically located nuclei. The surrounding myelin sheaths appear white, encasing nerve fibers extending from the ganglion

This histological slide presents a dorsal root ganglion (DRG) of the spinal cord, stained in shades of purple. The DRG contains large, round neuronal cell bodies (somata) with visible nuclei, some of which are centrally located while others are eccentric. These sensory neurons are surrounded by small, dark-staining satellite cells that provide support and regulate the neuronal environment. Extending from the ganglion, nerve fibers appear as elongated structures, with their myelin sheaths appearing white, creating a contrast against the purple-stained background. The white spaces surrounding the axons correspond to the unstained myelin, which insulates and speeds up nerve conduction. The overall structure highlights the sensory function of the DRG, where primary afferent neurons transmit sensory information to the spinal cord

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