Corpora

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Corpus luteum

The corpus luteum is a temporary structure. It forms in the ovary after ovulation. The corpus luteum develops from the remnants of the ovarian follicle. Histologically, it is characterized by a highly vascularized structure. It is composed mainly of two types of lutein cells. These are granulosa lutein cells and theca lutein cells. Granulosa lutein cells are large and pale-staining. They are located centrally. These cells originate from the granulosa cells of the follicle. They primarily produce progesterone and some estrogens. Theca lutein cells are smaller and darker-staining. They are found more peripherally. These cells arise from the theca interna. They also contribute to steroid hormone production, especially androgens, which can be converted to estrogens.

Corpus albicans

If pregnancy does not occur, the corpus luteum degenerates into the corpus albicans, a fibrous scar composed largely of collagen. However, if fertilization and implantation occur, the developing embryo releases human chorionic gonadotropin (hCG). This hormone maintains the corpus luteum. It continues secreting progesterone, which is essential for early pregnancy.

Histological slide showing a corpus luteum in cross-section, stained light pink. The corpus luteum exhibits a convoluted, lobular structure with a central medullary area. The cortical region appears cellular, extending radially toward the periphery. Irregular boundaries and tissue density variations are present, enhancing depth. The overall composition is centered, highlighting the anatomical features.
Figure 1 Microscopic view of a corpus luteum in an ovary. Light pink-stained tissue with a central, lighter-colored region.
Histological image of the corpus luteum, displaying a highly vascularized structure with granulosa and theca lutein cells.
Figure 2 Histological image of the corpus albicans.

Figure 1 & 2: Ovary, H&E, 40X Slide 236a
All by University of Michigan Histology, licensed under CC BY-NC-SA 3.0.

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