Digestive System: Glossary

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3–5 minutes

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Adventitia – The outermost connective tissue layer of an organ, such as the esophagus, which binds it to surrounding structures.

Anus – The terminal opening of the digestive tract through which feces are expelled.

Appendix – A small, finger-like pouch attached to the cecum, thought to play a role in immune function.

Bile – A digestive fluid produced by the liver and stored in the gallbladder; it helps emulsify fats for digestion.

Bilirubin – A pigment derived from the breakdown of hemoglobin; it gives bile its yellow-green color and is excreted in bile.

Bolus – A rounded mass of food mixed with saliva that is ready for swallowing.

Brush Border – The microvilli-covered surface of intestinal epithelial cells, increasing surface area for nutrient absorption.

Chief Cells – Gastric cells that secrete pepsinogen, an inactive enzyme that is converted into pepsin for protein digestion.

Cholesterol – A lipid molecule that is a key component of cell membranes and a precursor for bile acids and steroid hormones.

Chyme – A semi-fluid mixture of partially digested food and digestive juices that moves from the stomach into the small intestine.

Circular Folds (Plicae Circulares) – Permanent folds in the small intestine that increase surface area for nutrient absorption.

D Cells – Cells in the stomach and pancreas that secrete somatostatin, which inhibits gastric acid secretion.

Duodenum – The first section of the small intestine where most digestion occurs; it receives chyme, bile, and pancreatic enzymes.

Epiglottis – A flap of cartilage that covers the trachea during swallowing to prevent food from entering the airway.

Esophagus – The muscular tube that transports food from the pharynx to the stomach via peristalsis.

Feces – Solid waste material formed in the large intestine and expelled through the anus.

Fundus – The dome-shaped upper part of the stomach that stores undigested food and gases.

G Cells – Gastric cells that secrete gastrin, a hormone that stimulates acid production.

Gallbladder – A small organ beneath the liver that stores and releases bile into the small intestine.

Gastrin – A hormone that stimulates gastric acid secretion and motility.

Gastroesophageal – Relating to the stomach and esophagus, often used in reference to the gastroesophageal junction or reflux disease.

Haustrum – A pouch-like structure in the large intestine that helps move fecal material.

Hepatic Portal System – A network of veins that carry nutrient-rich blood from the digestive organs to the liver.

Hepatic Portal Vein – The main vein that transports blood from the digestive tract to the liver for processing.

Hepatocytes – Liver cells responsible for detoxification, metabolism, and bile production.

Ileum – The last section of the small intestine, responsible for absorbing vitamin B12 and bile salts.

Intestinal Crypts (Crypts of Lieberkühn) – Glandular structures in the small intestine that produce digestive enzymes and new epithelial cells.

Jejunum – The middle section of the small intestine, primarily responsible for nutrient absorption.

Kupffer Cells – Specialized macrophages in the liver that help remove pathogens and old red blood cells.

Lacteal – A lymphatic vessel within a villus that absorbs dietary fats.

Liver – A large organ that produces bile, detoxifies blood, and stores nutrients.

Mastication – The process of chewing food to break it down into smaller pieces.

Mesentery – A fold of peritoneum that supports and connects the intestines to the abdominal wall.

Mesocolons – Extensions of the peritoneum that anchor parts of the large intestine to the abdominal wall.

Microvilli – Tiny projections on the surface of epithelial cells that increase surface area for absorption.

Mouth – The opening of the digestive tract where food enters and mastication begins.

Mucosa – The innermost lining of the digestive tract that contains mucus-secreting cells for protection and absorption.

Muscularis Externa – A smooth muscle layer of the digestive tract responsible for peristalsis and segmentation.

Myenteric Plexus – A network of nerves within the muscularis externa that controls digestive tract motility.

Omental Appendages – Small, fat-filled pouches attached to the colon, with an unclear function.

Omentum – A fold of peritoneum that contains fat and blood vessels, providing protection and support to abdominal organs.

Pancreas – A gland that produces digestive enzymes and hormones like insulin and glucagon.

Parietal Cells – Cells in the stomach that secrete hydrochloric acid (HCl) and intrinsic factor, essential for vitamin B12 absorption.

Peristalsis – Rhythmic contractions of smooth muscle that move food through the digestive tract.

Peritoneum – A serous membrane that lines the abdominal cavity and covers the abdominal organs.

Pharynx – The muscular passageway connecting the mouth to the esophagus and larynx.

Pyloric – Relating to the pylorus, the region of the stomach that connects to the small intestine.

Rectum – The final section of the large intestine, where feces are stored before elimination.

Retroperitoneal – Referring to organs located behind the peritoneum, such as the kidneys and pancreas.

Rugae – Folds in the stomach lining that allow expansion when food enters.

Submucosal Plexus – A network of nerves in the submucosa that regulates glandular secretions and blood flow in the digestive tract.

Teniae Coli – Three bands of smooth muscle along the large intestine that help move feces.

Villi – Finger-like projections in the small intestine that increase surface area for absorption.

List of terms