Medulla Oblongata

Time To Read

3–4 minutes

Date Last Modified

The Brain Stem

This is a great picture of what was formerly called the brainstem. It’s now called the diencephalon metencephalon. You can use whatever cephalon word that you like. Whatever you collectively call these units does not diminish from the fact that they act separately. From superior to inferior we have the midbrain the ponds and the medulla oblongata. You can see that the medulla oblongata transitions into the spinal cord at its inferior most border. The blue areas in this diagram are the 4th ventricle and the cerebral aqueduct. This open area contains cerebrospinal fluid. It is continuous with the central canal known from spinal cord cross sections.


Medulla Oblongata Anatomy

The transverse section here on the left is a very superior cut of the medulla oblongata. The one on the right is more inferior. It is almost at the point where it changes over into the spinal cord.  This transverse section on the left is so superior, this open area is the 4th ventricle.  This inferior transverse section has what will become the central canal.  This butt crack is the anterior median fissure and thus the ventral side and this is the dorsal side.  There are two main anatomical structures of the medulla oblongata that are noteworthy.  The pyramids consist of motor neurons. They descend into the white matter motor pathways of the spinal cord. This is similar to the cerebrospinal tract.  These pyramids are directly lateral to the anterior median fissure.  The other noteworthy anatomical structure is the olives.  They are these squiggly lines here.  I don’t know what they do.  I’m kidding… These form a connection to the Purkinje cells of the cerebellum.  These olives are capable of sending sensory information to the cerebellum.


Medulla Oblongata White Matter

The white matter of the medulla oblongata consists of myelinated axons of spinal tracts. It also includes myelinated axons of cranial nerves, as with many of the other structures of the brain stem.  The white matter tracts that run through the medulla oblongata include the lateral spinothalamic tract, which carries conscious information. The corticospinal tract carries both conscious and subconscious information to skeletal muscles. 

The nuclei of cranial nerves, VIII, IX, X, and XII are housed in the medulla oblongata.  Go ahead and try….can  you recall what those cranial nerves are called?  VIII…IX…X…XII

Vestibulocochlear, glossopharyngeal, vagus, hypoglossal.


Medulla Oblongata Gray Matter

OK, back to gray matter.  Sorry, I had to do the pyramids and olives before the white matter. I needed to finish the white matter before discussing this function of the gray matter of the medulla oblongata.  Check out this picture on the right.  This hand is receiving a sensation.  An action potential travels up the red neuron. It is the 1st order neuron in this sequence. Here, it enters into an ascending spinal tract.  The red neuron ends in the medulla oblongata. It synapses with another neuron, the neuron of the 2nd order. This neuron then brings the action potential to, say, the thalamus.  In the thalamus, the 2nd order neuron synapses with a 3rd order neuron. This 3rd order neuron takes the action potential to the correct place in the brain. The brain then assigns some perception to the sensation.  This neuron of the second order is important.  First, it is an interneuron because it is completely contained in the CNS.  Secondly, it form a projection fiber, which is a myelinated axon projecting from these brain stem structures into the cerebrum.  You might be examining this diagram. You might say, “But, Amy, that blue neuron of the second order does that too!”  Yes, it does and it is a projection fiber too, but it takes a different pathway to get there.  This sequence of blue neurons is moving up the spinothalamic tract.  This is just an example, I don’t know that for sure. 


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