Midbrain

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3–4 minutes

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Midbrain Anatomy

This picture is a very common transverse section of the midbrain. This little star shaped or + shaped hole is the cerebral aqueduct. This is that very very small canal connecting the 3rd and 4th ventricles. Sometimes in growing children, this very narrow cerebral aqueduct becomes pinched. This restricts the flow of CSF from the choroid plexuses to the spinal cord.  In this case, CSF will build up in the brain.  A neural shunt is an artificial support that can hold open the cerebral aqueduct.  These shunts are similar to the stents used to hold open arteries.


Superior and Inferior Colliculi

These two bulges come off the dorsal side of the midbrain. They are only two of the four bulges. These are called the colliculi. The top 2 bulges are the superior colliculus and the bottom 2 as the inferior colliculus.

The superior colliculus Is involved in tracking eye movements and objects in relation to your position. It coordinates reflexive head movements in response to what you see.  These superior colliculi are hardwired to the optic nerve, cranial nerve II and receive tons of visual information to process.. The inferior colliculus consolidates auditory input to determine where a sound was made in relationship to your position.

Sports like baseball and past-times like listening to music can stimulate these areas in a growing child.  This is why sports such as T-ball and soccer can help develop these areas. 


Midbrain’s Motor Control

The red nucleus is grey matter kind of on either side of the crotch of the midbrain here. The red nucleus is highly involved with fine motor control of the hands. The red nucleus collaborates with the cerebellum but also with the basal nuclei.

The substantia nigra are these swaths of black that you see on this picture. The substantia nigra’s function is to make dopamine. When it makes dopamine though it produces melanin as a byproduct. The substantial nigra on someone should be nice and dark with that neuromelanin. On the other side of the midbrain is an example. It shows how the substantia nigra looks in someone with Parkinson’s disease.

They would have a very lightly colored substantial nigra. This is because the root cause of Parkinson’s disease is the inability to make dopamine. Now when everything’s functioning correctly, dopamine made in your substantia nigra is used by the red nucleus. It is also used by your basal nuclei and your thalamus to inhibit unnecessary movements. One such unnecessary movement is a tremor. If you don’t have tremors, then your substantia nigra is likely making enough dopamine. This amount is sufficient for your basal nuclei and other parts of your brain to use. With Parkinson’s, the reduced ability to create dopamine for the basal nuclei causes a tremor. This tremor usually appears in the hands first because that’s where fine motor control exists.


Midbrain White/Gray Matter

There are two tabs coming off of the ventral side of the midbrain. There’s a lot of anatomy concerned with these tabs. In general, they are called the cerebral peduncles.  Cerebral peduncles should not be confused with cerebellar peduncles that came off the pons. Cerebral peduncles physically support the big brain hat.  The peduncles are made up of myelinated axons of more than a few tracts.

These are mostly myelinated axons that are the upper motor neurons of descending motor pathways. Axons of the corticospinal tract carry information from the primary motor cortex. They transmit it to the appropriate level of the spinal cord. Axons of the reticulospinal tract also facilitate this output. Those axons pass through these cerebral peduncles.


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