Cardiac

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A magnified view of cardiac muscle tissue as seen on a histological slide. The image exhibits striated muscle fibers running horizontally across the frame, purple-stained nuclei are squished between sarcolemma.
Figure 1: Cardiac muscle tissue under a microscope, showing intercalated discs

Cardiac muscle, like smooth muscle, is involuntarily controlled.  Unlike the sheets of smooth muscle, cardiac muscle fibers are branching cylinders that are connected branch to branch.  These unique connections, called intercalated discs, firmly attach two adjacent cells, but also allow ion exchange between the cells.

Cells

Cardiac muscle fibers have striations. These are created by the dark and light banding of the myofibrils packed into the cells. They are just like skeletal muscle fibers and can be easily confused for skeletal muscle.  There is a subtle difference between the squished appearance of the darkly-stained nuclei of skeletal and cardiac muscle fibers. The nuclei of skeletal muscle fibers appear more flattened than the nuclei of cardiac muscle fibers. The main differentiating characteristic is the intercalated discs that are perpendicular to the sarcolemma of the cardiac muscle fibers.

Intercalated Discs

Cardiac muscle fibers have intercalated discs.  These are where two adjacent cells come into contact.  An intercalated disc consists of desmosomes and gap junctions.  A desmosome is a very firm connecting proteins between the two cells.  A gap junction is a little channel that allows these cells to exchange cytoplasm.  When one of these cells has an action potential, it shares that electrical current with the adjacent cell. The current travels via the gap junction.  Immediately following the current, the first cell contracts.  This contract also moves the adjacent cell, since they are attached.  This lets the heart squeeze blood through it. It’s similar to how you would squeeze a tube of toothpaste to expel that last little bit.  

A magnified view of cardiac muscle tissue as seen on a histological slide. The image exhibits striated muscle fibers running horizontally across the frame, purple-stained nuclei are squished between sarcolemma.
Figure 2: Cardiac muscle tissue under a microscope, showing intercalated discs perpendicular to the sarcolemma.
A magnified view of cardiac muscle tissue as seen on a histological slide. The image exhibits striated muscle fibers running horizontally across the frame, stained a vibrant red. White spaces are visible between the fibers.
Figure 3: Cardiac muscle tissue under a microscope, showing striated fibers.

Figure 1: Heart, ventricle, H&E, 40X Slide 098-1
Figure 2: Heart, ventricle, H&E, 40X Slide 057
Figure 3: Heart wall, trichrome stain, 40X Slide 098-N
All by University of Michigan Histology, licensed under CC BY-NC-SA 3.0.

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