Blood Histology

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Microscopic image exhibiting a field of erythrocytes, stained pink against a bright white background. The cells are mostly normocytic, but some size and shape variation is present. A few dark blue inclusions (likely platelets or staining artifacts) are distributed sporadically. This is a high-magnification view, typical of a blood smear analysis.

Also known as red blood cells, these hemoglobin backpacks are designed to maximize the surface area to volume ratio.

Microscopic image exhibiting a field of erythrocytes, stained pink against a bright white background. The cells are mostly normocytic, but some size and shape variation is present. A few dark blue inclusions (likely platelets or staining artifacts) are distributed sporadically. This is a high-magnification view, typical of a blood smear analysis.

Involved in blood clotting, these tiny little fragments of a larger cells can cause a profound difference if not in homeostasis.

Light microscopy image of stained human blood. Many anucleate, biconcave, pink erythrocytes are dispersed across a light background. Two larger, speckled neutrophils with multi-lobed, dark purple nuclei are visible. The neutrophils appear round with a slightly textured and gray-violet cytoplasm. Illumination appears even.

The EMTs and first responders of the immune system

A microscopic image shows a blood smear with a white background. Many pink/red erythrocytes (red blood cells) fill most of the image. A single, prominent lymphocyte, stained a darker purple/blue, is located near the image center containing a dark spot suggesting the nucleus. Small purple spots near the lymphocyte may be platelets.

Lymphocytes come in a variety of flavors: T cell, B cell, and NK cells. These are second line defenders of the immune system.

Microscopic image of stained blood cells on a light background. Erythrocytes (red blood cells) appear as uniformly stained pinkish-red biconcave discs. A monocyte is centrally located; it's larger with a light blue cytoplasm and large, lobulated dark purple/blue colored nucleus, typical kidney-shaped. Isolated dark purple specks also scattered through the image. The cells are densely packed.

Circulating in blood and gobbling up invaders, many monocytes will later move into specific tissues and become resident macrophages.

Microscopic view. Red blood cells, stained pink, are distributed across a white background. At the center, an eosinophil cell stands out with its prominent blue and pink granules. Smaller blue platelets appear throughout the frame. The overall composition is a close-up view, capturing the cellular structure in detail.

Named for the red cytoplasm that differentiates these leukocytes from the other, eosinophils are key in fighting parasites.

Microscopic blood smear image: two large, round basophils heavily stained in dark purple occupy the upper-right and center of the frame. Their granulated texture is prominent. Numerous biconcave red blood cells appear pink and are distributed around the basophils against a plain, pale white background. The composition suggests a clinical or research context.

Friend or foe? These cells are rich with vesicles of histamine and can really cause some damage if they all decide to release it at once.

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The purple tab on the right opens a panel with information and links.

All Figures: Slide 86X Human blood smear, Giemsa stain, 86X scan from hematopathology normals collection
All by University of Michigan Histology, licensed under CC BY-NC-SA 3.0.

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