Vas Deferens

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The ductus or vas deferens traverses superiorly from the testes. It is encased in the spermatic cord along with nerves and blood vessels. The ductus or vas deferens travels over the public symphysis. It then moves up and around the bladder. After that, it goes through the prostate gland and finally connects with the ureters. Sperm in the ductus (vas) deferens should be fully mature, with functional flagella. However, the ductus (vas) deferens is lined with pseudostratified ciliated columnar epithelial cells. The uniform waving motion of the cilia moves the sperm forward. Alternating contractions of the thick layer of smooth muscle surrounding the ductus (vas) deferens help propel spermatozoa. They push the sperm toward the urethra.

Microscopic histological cross-section of a spermatic cord, viewed at an angle. The image is dominated by pink and white tones. Dominant circular structures represents the artery, while other smaller, tightly packed circular features represents the veins, surrounded by white spaces where white connective tissue is.
Figure 1: Low magnification of spermatic cord with blood vessels, the genitofemoral nerve and the vas deferens.
Photomicrograph of spermatic cord, hematoxylin and eosin (H&E) stain. Shows a cross-section with circular arrangement of cells. Lumen visible as clear or lightly stained space, surrounded by pink and purple stained cells. Cell nuclei are visible, indicating cellular structure. Magnification level not specified.
Figure 2: High magnification vas deferens showing pseudostratified ciliated columnar epithelium and spermatozoa in the lumen and surrounding smooth muscle

Figure 1 & 2: Penis cross section, human, H&E, 40X Slide 2986
All by University of Michigan Histology, licensed under CC BY-NC-SA 3.0.

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