ANATOMY & PHYSIOLOGY II · MODULE 20
One leaking filter behind every number
Swollen ankles, a low calcium, and a drift toward acidA substance that releases hydrogen ions (H⁺) in solution. — three findings, three pieces of advice, one visit. This module builds fluid, electrolyte, and acid-base physiologyThe study of how the body functions. and shows that all three are the same failure read from different angles.
The findings this module reads together
Cut the salt, take calcium, drink more waterThe universal solvent essential for life.. On its own each instruction sounds reasonable. But her edemaExcess fluid in interstitial spaces. means fluid has left the vessels for the tissues, and her albuminA plasma protein that helps maintain osmotic pressure and transport substances. is low because she is losing it through a damaged filter.
Low albumin drops oncotic pressureThe force exerted by gases in the respiratory system, affecting airflow and gas exchange., so fluid leaks. Roughly half of blood calcium rides on albumin, so the total calcium reads low while the free calcium is fine. And a failing kidney stops reclaiming bicarbonate(HCO₃⁻) – A crucial buffer in blood that helps maintain pH balance; formed when carbon dioxide react, so the pHA measure of hydrogen ion concentration in a solution. drifts. Three findings, one leaking filter.
PATIENT CHART · STINA · CHART CLUE #20
- Exam — Swollen ankles, pitting edema
- Labs — Low albumin
- Labs — ‘Low’ total calcium
- Labs — Low bicarbonate, acid drift
Seven parts, one chart
Each part opens with a finding from Stina’s chart and asks you to commit to a prediction before any video plays, then alternates short videos with H5P activities. Work them in order.
20.2
Fluid Compartments & Water Movement
Where body water sits and what moves it.
FLUID COMPARTMENTS
20.4
Electrolytes & Corrected Calcium
Why a low total calcium can mean nothing at all.
ELECTROLYTES
20.7
One Filter, Not Three Problems
A scattered handful of lab flags, collapsed into one cause.
CHART CLUE #20
◆
The Evidence Behind the Case
Every step of this module’s reasoning, paired with the peer-reviewed literature behind it.
REFERENCES
What you’ll be able to do
By the end of Module 20 you will be able to:
1
Describe the body’s fluid compartmentsDivisions of body water: intracellular, extracellular, and transcellular. and the forces that move water between them.
2
Explain hydrostatic and oncotic pressure and predict the effect of hypoalbuminemia.
3
Identify the major electrolytes and calculate an albumin-corrected calcium.
4
Explain the bicarbonate buffer systemThe main buffer in ECF, involving HCO₃⁻ and H₂CO₃. and the roles of lung and kidney in pH control.
5
Distinguish metabolic from respiratory acid-base disturbances.
6
Integrate edema, hypoalbuminemia, and acidosisA condition where blood pH falls below 7.35. as consequences of one renal lesion.
Hop to:
← Familial Mediterranean Fever — case home
All pages for Module 20 — Fluids, Electrolytes & Acid–Base Balance
20.0 Module Overview
20.1 The Swollen Ankles That Point Back to the Kidney
20.2 The Body’s Fluid Compartments & Water Movement
20.3 Hydrostatic vs Oncotic Pressure
20.4 The Major Electrolytes & the Albumin-Corrected Calcium
20.5 Acid-Base Balance & the Bicarbonate Buffer System
20.6 Metabolic Acidosis from a Failing Kidney
20.7 One Filter, Not Three Problems
20.8 Conclusion and Assessment
20.9 Evidence Behind the Case
All Modules
- Anatomical Language, Membranes & Homeostasis
- Just Enough Chemistry
- The Cell & Its Transport
- Making Cells & Proteins
- The Integumentary System
- The Skeletal System
- The Muscular System
- Nervous Tissue & the Senses
- The Spinal Cord
- The Brain & the Blood–Brain Barrier
- The Autonomic Nervous System
- Special Senses (in developmentThe process of growth and differentiation.)
- The Endocrine System
- Blood
- The Heart
- Blood Vessels
- The Digestive System
- The Respiratory System
- The Urinary System
- Fluids, Electrolytes & Acid–Base Balance
- The Reproductive System
- The Immune System
List of terms
- acid
- physiology
- water
- edema
- albumin
- pressure
- bicarbonate
- pH
- base
- fluid compartments
- bicarbonate buffer system
- acidosis
- development