ANATOMY & PHYSIOLOGY II · MODULE 14
The acute-phase response as a slow fuse
Reactive thrombocytosis, years of raised inflammatory markers, and one red-cell finding that fits nothing. Filed separately they look like odd, harmless labs. This module builds blood and reads them as one sustained alarm.
The findings this module reads together
Stina’s chronic labs have a shape: platelets reactive and high, markers up for years, and an inappropriately high erythropoietin(EPO): A hormone produced by the kidneys that stimulates erythropoiesis. that nobody could place. Each was noted; none was chased.
The acute-phase response is meant to be brief. Hers never switched off, and serum amyloid A has been produced faithfully the whole time — a slow fuse, quietly seeding the amyloid that will surface in her gut and her kidneys. One red-cell finding, meanwhile, points somewhere else entirely.
PATIENT CHART · STINA · CHART CLUE #14
- Years — Inflammatory markers elevated
- Labs — Reactive thrombocytosis
- Labs — Inappropriately high EPO
- Consequence — SAA feeding amyloid
Seven parts, one chart
Each part opens with a finding from Stina’s chart and asks you to commit to a prediction before any video plays, then alternates short videos with H5P activities. Work them in order.
14.1
Resetting Set Points
The bridge from hormones into the tissue that carries them.
TRANSITION
14.2
The Red Cell Finding That Fits Nothing
One count that points outside the main story.
ERYTHROCYTOSIS
14.3
What’s in Blood
Plasma, formed elementsThe cellular components of blood, including red blood cells, white blood cells, and platelets., and what each does.
BLOOD COMPOSITION
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The Evidence Behind the Case
Every step of this module’s reasoning, paired with the peer-reviewed literature behind it.
REFERENCES
What you’ll be able to do
By the end of Module 14 you will be able to:
1
Describe the composition of blood and the functions of plasmaThe liquid component of blood. and formed elements.
2
Explain erythropoiesisThe process of red blood cell production., the role of erythropoietin, and iron handling.
3
Identify the five leukocytes and describe their roles in defense.
4
Describe hemostasis from vascular spasm through clot retraction.
5
Explain the acute-phase response and the behavior of its markers.
6
Relate sustained serum amyloid A production to AA amyloid depositionThe process of bone matrix formation by osteoblasts..
Hop to:
← Familial Mediterranean Fever — case home
All Modules
- Anatomical Language, Membranes & Homeostasis
- Just Enough Chemistry
- The Cell & Its Transport
- Making Cells & Proteins
- The Integumentary System
- The Skeletal System
- The Muscular System
- Nervous Tissue & the Senses
- The Spinal Cord
- The Brain & the Blood–Brain Barrier
- The Autonomic Nervous System
- Special Senses (in developmentThe process of growth and differentiation.)
- The Endocrine System
- Blood
- The Heart
- Blood Vessels
- The Digestive System
- The Respiratory System
- The Urinary System
- Fluids, Electrolytes & Acid–Base Balance
- The Reproductive System
- The Immune System
List of terms
- erythropoietin
- formed elements
- plasma
- erythropoiesis
- deposition
- development